What you should know
Possible symptoms
Syphilis may begin with a sore or ulcer, then later cause rash, fever, or no obvious symptoms.
Testing
Testing may involve a blood test, especially when symptoms are not obvious.
Treatment
Syphilis is usually treated with prescription medication. Early treatment is important.
Follow-up care
A clinician can help you understand your result, treatment, and whether a partner may also need care.
When not to delay
Seek prompt assessment if you are pregnant or may be pregnant, or have a partner with syphilis. New changes in vision, hearing or nerve-related symptoms need urgent medical assessment. Follow-up blood tests help a clinician assess the response to treatment.
A painless sore still needs attention
A syphilis sore may not hurt, and it may heal without the infection being cured. Symptoms can later change or disappear. A blood test and clinical history help establish the diagnosis and the right treatment plan.
How syphilis support works
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Tell us about your symptoms, exposure, or questions about testing.
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Learn what the symptoms may mean and what test may be appropriate.
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Get guided to testing or treatment support when needed.
Common questions
Can syphilis start without symptoms?
Yes. Some people do not notice symptoms at first.
How is syphilis treated?
Syphilis is usually treated with prescription medication.
Is syphilis serious?
It can become serious if not treated early, so testing matters.